AIMC Topic: Receptor, Platelet-Derived Growth Factor alpha

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A deep-learning model for predicting tyrosine kinase inhibitor response from histology in gastrointestinal stromal tumor.

The Journal of pathology Feb 14, 2025
Over 90% of gastrointestinal stromal tumors (GISTs) harbor mutations in KIT or PDGFRA that can predict response to tyrosine kinase inhibitor (TKI) therapies, as recommended by NCCN (National Comprehensive Cancer Network) guidelines. However, gene seq...
Humans Female Aged Male Middle Aged Deep Learning Treatment Outcome Mutation Gastrointestinal Neoplasms Gastrointestinal Stromal Tumors Imatinib Mesylate Pyrazoles Protein Kinase Inhibitors Pyrroles Triazines Proto-Oncogene Proteins c-kit Tyrosine Kinase Inhibitors Receptor, Platelet-Derived Growth Factor alpha
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