AIMC Topic: Septins

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High-content high-resolution microscopy and deep learning-assisted analysis reveals host and bacterial heterogeneity during infection.

eLife
is a Gram-negative bacterial pathogen and causative agent of bacillary dysentery. is closely related to but harbours a virulence plasmid that encodes a type III secretion system (T3SS) required for host cell invasion. Widely recognised as a paradi...

Precise measurement of nanoscopic septin ring structures with deep learning-assisted quantitative superresolution microscopy.

Molecular biology of the cell
The combination of image analysis and superresolution microscopy methods allows for unprecedented insight into the organization of macromolecular assemblies in cells. Advances in deep learning (DL)-based object recognition enable the automated proces...