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Skin Diseases, Genetic

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Accurate stratification between VEXAS syndrome and differential diagnoses by deep learning analysis of peripheral blood smears.

Clinical chemistry and laboratory medicine
OBJECTIVES: VEXAS syndrome is a newly described autoinflammatory disease associated with somatic mutations and vacuolization of myeloid precursors. This disease possesses an increasingly broad spectrum, leading to an increase in the number of suspec...

Deep Learning-Based Blood Abnormalities Detection as a Tool for VEXAS Syndrome Screening.

International journal of laboratory hematology
INTRODUCTION: VEXAS is a syndrome described in 2020, caused by mutations of the UBA1 gene, and displaying a large pleomorphic array of clinical and hematological features. Nevertheless, these criteria lack significance to discriminate VEXAS from othe...