AIMC Topic: Ubiquitin-Activating Enzymes
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Deep Learning-Based Blood Abnormalities Detection as a Tool for VEXAS Syndrome Screening.
International journal of laboratory hematology
Sep 14, 2024
INTRODUCTION: VEXAS is a syndrome described in 2020, caused by mutations of the UBA1 gene, and displaying a large pleomorphic array of clinical and hematological features. Nevertheless, these criteria lack significance to discriminate VEXAS from othe...
Altered Expression Patterns of the Sumoylation Enzymes E1, E2 and E3 Are Associated with Glucose Oxidase- and UVA-Induced Cataractogenesis.
Current molecular medicine
Jan 1, 2018
PURPOSE: Protein sumoylation is a well established regulatory mechanism that regulates chromatin structure and dynamics, cell proliferation and differentiation, stress response and cell apoptosis. In the vertebrate eye, we and others have shown that ...
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