AIMC Topic: Vaccine Development

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Vaccine design and development: Exploring the interface with computational biology and AI.

International reviews of immunology
Computational biology involves applying computer science and informatics techniques in biology to understand complex biological data. It allows us to collect, connect, and analyze biological data at a large scale and build predictive models. In the t...

Enhancing tuberculosis vaccine development: a deconvolution neural network approach for multi-epitope prediction.

Scientific reports
Tuberculosis (TB) a disease caused by Mycobacterium tuberculosis (Mtb) poses a significant threat to human life, and current BCG vaccinations only provide sporadic protection, therefore there is a need for developing efficient vaccines. Numerous immu...

Scoping Review of Deep Learning Techniques for Diagnosis, Drug Discovery, and Vaccine Development in Leishmaniasis.

Transboundary and emerging diseases
, a single-cell parasite prevalent in tropical and subtropical regions worldwide, can cause varying degrees of leishmaniasis, ranging from self-limiting skin lesions to potentially fatal visceral complications. As such, the parasite has been the subj...

Literature Mining and Mechanistic Graphical Modelling to Improve mRNA Vaccine Platforms.

Frontiers in immunology
RNA vaccines represent a milestone in the history of vaccinology. They provide several advantages over more traditional approaches to vaccine development, showing strong immunogenicity and an overall favorable safety profile. While preclinical testin...

Mapping the landscape of AI and ML in vaccine innovation: A bibliometric study.

Human vaccines & immunotherapeutics
With the rapid advancement of artificial intelligence (AI) and machine learning (ML) technologies, their applications in the medical field have expanded significantly. Particularly in vaccine innovation, AI and ML have shown considerable potential. T...

Applications of artificial intelligence and nanotechnology in vaccine development.

International journal of pharmaceutics
Vaccines have long been crucial in safeguarding public health by preventing and controlling infectious diseases. However, traditional vaccine development methods face challenges in efficiency, cost, and response time to emerging pathogens. Recent pro...

Application of in-silico approaches in subunit vaccines: Overcoming the challenges of antigen and adjuvant development.

Journal of controlled release : official journal of the Controlled Release Society
Subunit vaccines are crucial in preventing modern diseases due to their safety, stability, and ability to elicit targeted immune responses. However, challenges in antigen and adjuvant design hinder their development. Recent advancements in in-silico ...

Artificial intelligence in vaccine research and development: an umbrella review.

Frontiers in immunology
BACKGROUND: The rapid development of COVID-19 vaccines highlighted the transformative potential of artificial intelligence (AI) in modern vaccinology, accelerating timelines from years to months. Nevertheless, the specific roles and effectiveness of ...

An Integrated Approach to Develop a Potent Vaccine Candidate Construct Against Prostate Cancer by Utilizing Machine Learning and Bioinformatics.

Cancer reports (Hoboken, N.J.)
BACKGROUND: Prostate cancer is the most common malignancy among males. Prostaglandin G/H synthase (PGHS) is an essential enzyme in the synthesis of prostaglandins, and its activation has been linked to many malignancies, including colorectal cancer.