PURPOSE: Patients are increasingly using artificial intelligence (AI) chatbots for health information. Evaluating their reliability for specialized topics, such as brachytherapy, is crucial for guiding their safe use. We assessed a readily accessible... read more
Unintended block of cardiac ion channels, particularly hERG (KV11.1), remains a key concern in drug development as disruption of ion channel function can lead to deadly arrhythmia. To assess proarrhythmic risk, we investigated how drugs interact with... read more
Journal of the mechanical behavior of biomedical materials
Dec 16, 2025
BACKGROUND: Dental implant longevity depends on the complex interaction between mechanical stability and biological osseointegration. While finite element analysis (FEA) provides valuable mechanical insight, it remains static and computationally expe... read more
Early and accurate identification of Brain Tumors (BT) is one of the most challenging problems due to the complex, non-Euclidean, and irregular characteristics of brain MRI data. Graph Signal Processing (GSP) offers a robust framework for accurately ... read more
ETHNOPHARMACOLOGICAL RELEVANCE: In non-small cell lung cancer (NSCLC), fatal outcomes predominantly result from metastatic dissemination, highlighting an urgent need for metastasis-directed therapies. Amentoflavone (AMF), a natural biflavonoid found ... read more
BACKGROUND: Existing models that use clinical history and cardiac imaging data remain inadequate for accurate prediction of the success of catheter ablation for atrial fibrillation (AF). Local strain in the left atrium (LA) from 4-dimensional compute... read more
International journal of pharmaceutics
Dec 16, 2025
The mutual benefits of surface engineering and crystal engineering led to the discovery of a pharmaceutical cocrystal with balanced biopharmaceutical properties. The surface engineering of a pharmaceutical API (Active Pharmaceutical Ingredient), name... read more
Biochemical and biophysical research communications
Dec 16, 2025
BACKGROUND: Multiple sclerosis (MS) and psoriasis are both immune-mediated inflammatory diseases. Previous studies have reported comorbidity between MS and psoriasis, but the underlying mechanisms remain unclear. This study aims to elucidate the shar... read more
PURPOSE: eHealth treatments have been developed for a range of conditions. They provide an accessible, cost-effective, and convenient model for clients and families to access treatment. The aim of this paper is to provide details and results of user ... read more
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