Biochemical and biophysical research communications
Dec 16, 2025
BACKGROUND: Multiple sclerosis (MS) and psoriasis are both immune-mediated inflammatory diseases. Previous studies have reported comorbidity between MS and psoriasis, but the underlying mechanisms remain unclear. This study aims to elucidate the shar...
Psoriasis is a systemic immune‑mediated skin disease, typically considered to be incurable. Identification of meaningful biomarkers has been a notable challenge in psoriasis prevention and management. The present study aimed to determine the signatur...
BACKGROUND: Over 300 million individuals worldwide live with Atopic Dermatitis and Psoriasis, which are among the most common chronic inflammatory skin diseases. Multimodal biomarkers are currently being developed using large-scale data and artificia...
Online health information (OHI) in dermatology often exceeds the recommended sixth-grade reading level, hindering patient comprehension. This study aimed to assess the utility of three artificial intelligence large language models (LLMs) - ChatGPT-3....
Di (2-ethylhexyl) phthalate (DEHP), a widely used plasticizer with known immunotoxic effects, has been suspected of aggravating inflammatory skin conditions, yet its role in autoimmune diseases such as psoriasis remains poorly defined. In this study,...
Clinica chimica acta; international journal of clinical chemistry
Sep 29, 2025
Psoriasis, a T-helper mediated chronic inflammatory autoimmune skin disease, has significant socioeconomic burden worldwide. Unfortunately, its etiology and underlying pathophysiology remains unclear. Although several biologics have substantially imp...
Due to their similar clinical presentations, the scarcity of competent dermatologists, and the urgency of diagnosis, the accurate diagnosis of dermatological conditions such as Psoriasis and Lichen Planus is challenging. This study introduces a novel...
BACKGROUND: The development of medical treatments has traditionally relied on researchers leveraging scientific knowledge to hypothesize disease mechanisms and identify therapeutic agents. However, the depletion of novel therapeutic targets has becom...
The Journal of investigative dermatology
Apr 10, 2025
Psoriasis is a chronic inflammatory disease with significant physical and psychological impacts. To overcome the limitations of single-modality artificial intelligence models in diagnosing inflammatory skin diseases, we propose a multimodal framework...
Psoriasis is a common chronic skin disorder with a polygenic background. It is widely acknowledged that Th17/IL-17A axis plays a key role in the pathogenesis of psoriasis. However, numerous regulatory genes upstream of the pathway remain undiscovered...
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