Definition and Validation of Prognostic Phenotypes in Moderate Aortic Stenosis.

Journal: JACC. Cardiovascular imaging
PMID: 39152961

Abstract

BACKGROUND: Adverse outcomes from moderate aortic stenosis (AS) may be caused by progression to severe AS or by the effects of comorbidities. In the absence of randomized trial evidence favoring aortic valve replacement (AVR) in patients with moderate AS, phenotyping patients according to risk may assist decision making.

Authors

  • Jonathan Sen
    Imaging Research laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia; Baker Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia; Western Health, Melbourne, Australia; Princess Alexandra Hospital, Brisbane, Australia.
  • Sudhir Wahi
    Princess Alexandra Hospital, Brisbane, Australia.
  • William Vollbon
    Statewide Cardiac Clinical Informatics Unit, Queensland Health, Brisbane, Australia.
  • Marcus Prior
    Statewide Cardiac Clinical Informatics Unit, Queensland Health, Brisbane, Australia.
  • Alex G C de Sá
    School of Chemistry and Molecular Biosciences, The Australian Centre for Ecogenomics, The University of Queensland, Brisbane, Queensland 4072, Australia.
  • David B Ascher
    Department of Biochemistry and Molecular Biology, University of Melbourne, Melbourne, Australia.
  • Quan Huynh
    Imaging Research laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.
  • Thomas H Marwick
    Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia; Baker Heart and Diabetes Institute, Melbourne, Australia.

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