Deep Learning Based Shear Wave Detection and Segmentation Tool for Use in Point-of-Care for Chronic Liver Disease Assessments.

Journal: Ultrasound in medicine & biology
PMID:

Abstract

OBJECTIVE: As metabolic dysfunction-associated steatotic liver disease (MASLD) becomes more prevalent worldwide, it is imperative to create more accurate technologies that make it easy to assess the liver in a point-of-care setting. The aim of this study is to test the performance of a new software tool implemented in Velacur (Sonic Incytes), a liver stiffness and ultrasound attenuation measurement device, on patients with MASLD. This tool employs a deep learning-based method to detect and segment shear waves in the liver tissue for subsequent analysis to improve tissue characterization for patient diagnosis.

Authors

  • Mohammad Honarvar
    Sonic Incytes Medical Corp., Vancouver, BC, Canada.
  • Julio Lobo
  • Caitlin Schneider
    Sonic Incytes Medical Corp., Vancouver, BC, Canada. Electronic address: Caitlin@sonicincytes.com.
  • Nathan Wolfe
    Vancouver, BC, Canada.
  • Samer Gawrieh
    Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, United States of America. Electronic address: sgawrieh@iu.edu.
  • Rohit Loomba
    From the Bioacoustics Research Laboratory, Department of Electrical and Computer Engineering (A.H., W.D.O.), and Department of Food Science and Human Nutrition (J.W.E.), University of Illinois at Urbana-Champaign, 306 N Wright St, Urbana, IL 61801; Department of Radiology (M.B., M.P.A.), Liver Imaging Group, Department of Radiology (E.H., C.B.S.), and NAFLD Research Center, Division of Gastroenterology, Department of Medicine (R.L.), University of California, San Diego, La Jolla, Calif; and Department of Ultrasound, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, Poland (M.B.).
  • Alnoor Ramji
    University of British Columbia, Division of Gastroenterology, Vancouver, BC, Canada.
  • Tarek Hassanein
    Southern California Liver Centers and Southern California Research Center, Coronado, CA, USA.
  • Eric M Yoshida
    University of British Columbia, Division of Gastroenterology, Vancouver, BC, Canada.
  • Emily Pang
    Vancouver General Hospital, Department of Radiology, Vancouver BC, Canada.
  • Michael P Curry
    Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
  • Nezam H Afdhal
    Beth Israel Deaconess Medical Center, Division of Gastroenterology, Boston, MA, USA.