Artificial intelligence-based personalized survival prediction using clinical and radiomics features in patients with advanced non-small cell lung cancer.

Journal: BMC cancer
Published Date: Nov 18, 2024

Abstract

BACKGROUND: Multiple first-line treatment options have been developed for advanced non-small cell lung cancer (NSCLC) in each subgroup determined by predictive biomarkers, specifically driver oncogene and programmed cell death ligand-1 (PD-L1) status. However, the methodology for optimal treatment selection in individual patients is not established. This study aimed to develop artificial intelligence (AI)-based personalized survival prediction model according to treatment selection.

Authors

  • Junji Koyama
    Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 4668550, Japan.
  • Masahiro Morise
    Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 4668550, Japan. morise.masahiro.u1@f.mail.nagoya-u.ac.jp.
  • Taiki Furukawa
    Nagoya University Hospital Medical IT Center, Nagoya University, Nagoya, Japan.
  • Shintaro Oyama
    Innovative Research Center for Preventive Medical Engineering, Nagoya University, Nagoya, Japan.
  • Reiko Matsuzawa
    Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 4668550, Japan.
  • Ichidai Tanaka
    Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 4668550, Japan.
  • Keiko Wakahara
    Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 4668550, Japan.
  • Hideo Yokota
    Cloud-Based Eye Disease Diagnosis Joint Research Team, RIKEN, Wako, Japan.
  • Tomoki Kimura
    Department of Radiation Oncology, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Yoshimune Shiratori
    Nagoya University Hospital Medical IT Center, Nagoya University, Nagoya, Japan.
  • Yasuhiro Kondoh
    Department of Respiratory Medicine and Allergy, Tosei General Hospital, Seto, Japan.
  • Naozumi Hashimoto
    Department of Respiratory Medicine, Fujita Health University, Toyoake, Japan.
  • Makoto Ishii
    Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 4668550, Japan.

Keywords

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