Identification of hub biomarkers in liver post-metabolic and bariatric surgery using comprehensive machine learning (experimental studies).

Journal: International journal of surgery (London, England)
PMID:

Abstract

BACKGROUND: The global prevalence of non-alcoholic fatty liver disease (NAFLD) is approximately 30%, and the condition can progress to non-alcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma. Metabolic and bariatric surgery (MBS) has been shown to be effective in treating obesity and related disorders, including NAFLD.

Authors

  • Zhehong Li
    Surgery Centre of Diabetes Mellitus, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
  • Liang Wang
    Information Department, Dazhou Central Hospital, Dazhou 635000, China.
  • Chenxu Tian
    Surgery Centre of Diabetes Mellitus, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
  • Zheng Wang
    Department of Infectious Diseases, Renmin Hospital of Wuhan University, Wuhan 430060, China.
  • Hao Zhao
    Surgery Centre of Diabetes Mellitus, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
  • Yao Qi
    Department of Vascular Surgery, The First Hospital of China Medical University, Shenyang, Liaoning, China.
  • Weijian Chen
    Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
  • Qiqige Wuyun
  • Buhe Amin
    Surgery Centre of Diabetes Mellitus, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
  • Dongbo Lian
    Surgery Centre of Diabetes Mellitus, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
  • Jinxia Zhu
    Institute of Land and Urban-Rural Development, Zhejiang University of Finance and Economics, Hangzhou 310018, China.
  • Nengwei Zhang
    Department of General Surgery, Beijing Shijitan Hospital, Capital Medical University/Peking University, Ninth Clinical Medical College, Beijing 100038, China.
  • Lifei Zheng
    Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
  • Guangzhong Xu
    Surgery Centre of Diabetes Mellitus, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.