Utilizing Machine Learning to Predict Liver Allograft Fibrosis by Leveraging Clinical and Imaging Data.

Journal: Clinical transplantation
PMID:

Abstract

BACKGROUND AND AIM: Liver transplant (LT) recipients may succumb to graft-related pathologies, contributing to graft fibrosis (GF). Current methods to diagnose GF are limited, ranging from procedural-related complications to low accuracy. With recent advances in machine learning (ML), we aimed to develop a noninvasive tool using demographic, clinical, laboratory, and B-mode ultrasound (US) features to predict significant fibrosis (METAVIR≥F2).

Authors

  • Madhumitha Rabindranath
    Transplant AI Initiative, Ajmera Transplant Program, University Health Network, Toronto, ON, Canada.
  • Yingji Sun
    Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada.
  • Korosh Khalili
    Department of Medical Imaging, University Health Network and University of Toronto, Toronto, Ontario, Canada.
  • Mamatha Bhat
    Transplant AI Initiative, Ajmera Transplant Program, University Health Network, Toronto, ON, Canada.