Deep learning-based automatic differentiation of acute angle closure with or without zonulopathy using ultrasound biomicroscopy: a comparison of diagnostic performance with ophthalmologists.

Journal: BMJ open ophthalmology
Published Date: May 22, 2025

Abstract

OBJECTIVE: This study aims to develop ultrasound biomicroscopy (UBM)-based artificial intelligence (AI) models for preoperative differentiation of acute angle closure (AAC) with or without zonulopathy and to compare their comprehensive diagnostic performance against ophthalmologists as a cross-sectional study.

Authors

  • Lu Cheng
    Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, Mathematics Building No. 3, Waterloo, ON, N2L 3G1, Canada.
  • Jiaming Hong
    School of Medical Information Engineering, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
  • Hailiu Chen
    Department of Ophthalmology, Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou, Guangdong, China.
  • Yunlan Ling
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, Guangdong, China.
  • Shufen Lin
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, Guangdong, China.
  • Jing Huang
    Department of Nephrology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
  • Ethan Wu
    Center for Advanced Eye Care, Carson City, Nevada, USA.
  • Yangyunhui Li
    Department of Ophthalmology, The Second People's Hospital of Foshan, Affiliated Foshan Hospital of Southern Medical University, Foshan, Guangdong, China.
  • Haotian Lin
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou.
  • Shaopeng Liu
    Department of Computer Science, Guangdong Polytechnic Normal University, Guangzhou, 510006, China; Guangdong Key Laboratory of Big Data Analysis and Processing, Guangzhou, 510006, China.
  • Jingjing Huang
    Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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