Evaluating the prognostic significance of artificial intelligence-delineated gross tumor volume and prostate volume measurements for prostate radiotherapy.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Published Date: Mar 22, 2025

Abstract

BACKGROUND AND PURPOSE: Artificial intelligence (AI) may extract prognostic information from MRI for localized prostate cancer. We evaluate whether AI-derived prostate and gross tumor volume (GTV) are associated with toxicity and oncologic outcomes after radiotherapy.

Authors

  • Jenna Adleman
    Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Lakeridge Health, Durham Regional Cancer Centre, Ontario, Canada. Electronic address: jadleman@lh.ca.
  • Pierre-Yves McLaughlin
    Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; The Ottawa Hospital, Ontario, Canada.
  • James M G Tsui
  • Ivan Buzurovic
    Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Thomas Harris
    National Institutes of Health, National Institute of Allergy and Infectious Diseases, Laboratory of Clinical Immunology and Microbiology, Neuroimmunological Diseases Section, Bethesda, MD, United States.
  • Julie Hudson
    Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Jaime Urribarri
    Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Daniel W Cail
    Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Paul L Nguyen
    Department of Radiation Oncology, Dana-Farber/Brigham Cancer Center, Boston.
  • Peter F Orio
    Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Leslie K Lee
    Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts.
  • Martin T King
    Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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