Potential Modulatory Roles of Gut Microbiota and Metabolites in the Associations of Macronutrient-to-Physical Activity Ratios With Dyslipidemia.

Journal: Journal of the American Heart Association
Published Date:

Abstract

BACKGROUND: Lifestyle factors toward diet and physical activity (PA) may directly influence the pathophysiology of dyslipidemia. However, the associations of the specific macronutrient-to-PA ratio with dyslipidemia, and the underlying mechanisms regarding gut microbiota and metabolites, remain largely unexplored.

Authors

  • Menghan Wang
    Key Laboratory for Disease Prevention and Control and Health Promotion of Shaanxi Province, Department of Epidemiology and Biostatistics, School of Public Health, Global Health Institute Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China.
  • Guoqing Ma
    College of Mechanical and Electrical Engineering, Changchun University of Science and Technology, Changchun 130022, Jilin, China.
  • Yunfeng Li
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles (UCLA), Los Angeles, California, USA.
  • Junqi Li
    Changzhou United Imaging Healthcare Surgical Technology Co., Ltd., Changzhou, China.
  • Jiawen Xie
    Key Laboratory for Disease Prevention and Control and Health Promotion of Shaanxi Province, Department of Epidemiology and Biostatistics, School of Public Health, Global Health Institute Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China.
  • Juan He
    Department of Clinical Laboratory Medicine Center, Inner Mongolia Autonomous Region People's Hospital, Hohhot, Inner Mongolia, China.
  • Chen He
    The Elderly of Treatment Department of Critical Medicine, The Frist Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, China.
  • Yifei He
    Department of EECS, University of Michigan, Ann Arbor, Michigan, USA.
  • Kaizhen Jia
    Key Laboratory for Disease Prevention and Control and Health Promotion of Shaanxi Province, Department of Epidemiology and Biostatistics, School of Public Health, Global Health Institute Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China.
  • Xinran Feng
    Key Laboratory for Disease Prevention and Control and Health Promotion of Shaanxi Province, Department of Epidemiology and Biostatistics, School of Public Health, Global Health Institute Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China.
  • Tian Tian
    Laboratory Animal Center College of Animal Science Jilin University Changchun China.
  • Hongbao Li
    Department of Physiology and Pathophysiology Xi'an Jiaotong University School of Basic Medical Sciences Xi'an China.
  • Xia Liao
    State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural Universitygrid.35155.37, Wuhan, China.
  • Xin Liu
    Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences, Weifang, Shandong, China.