A radiomics approach to distinguish Progressive Supranuclear Palsy Richardson's syndrome from other phenotypes starting from MR images.

Journal: Computer methods and programs in biomedicine
Published Date: Apr 13, 2025

Abstract

BACKGROUND AND OBJECTIVE: Progressive Supranuclear Palsy (PSP) is an uncommon neurodegenerative disorder with different clinical onset, including Richardson's syndrome (PSP-RS) and other variant phenotypes (vPSP). Recognising the clinical progression of different phenotypes would enhance the accuracy of detection and treatment of PSP. The study goal was to identify radiomic biomarkers for distinguishing PSP phenotypes extracted from T1-weighted magnetic resonance images (MRI).

Authors

  • Noemi Pisani
    Department of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, Italy.
  • Filomena Abate
    Center for Neurodegenerative Diseases (CEMAND), Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84131 Salerno, Italy.
  • Anna Rosa Avallone
    Center for Neurodegenerative Diseases (CEMAND), Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84131 Salerno, Italy.
  • Paolo Barone
    Center for Neurodegenerative Diseases (CEMAND), Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84131 Salerno, Italy.
  • Mario Cesarelli
  • Francesco Amato
    Department of Electrical Engineering and Information Technology, University of Naples "Federico II", Naples, Italy.
  • Marina Picillo
    Center for Neurodegenerative Diseases (CEMAND), Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84131 Salerno, Italy.
  • Carlo Ricciardi
    Department of Electrical Engineering and Information Technology, University of Naples "Federico II", Naples, Italy.

Keywords

External Resources

Popular Topics
Recent Journals