Integrating WGCNA and SVM-RFE identifies hub molecular biomarkers driving ischemic stroke progression.
Journal:
Neurological research
Published Date:
Apr 22, 2025
Abstract
BACKGROUND: Stroke is the second most common cause of death worldwide and the leading cause of long-term severe disability with neurological impairment worsening within hours after stroke onset and being especially involved with motor function. So far, there are no established and reliable biomarkers to prognose stroke. Early detection of biomarkers that can prognose stroke is of great importance for clinical intervention and prevention of clinical deterioration of stroke.