Screening of bioactive compounds and deep learning-driven quality control of Angong Niuhuang pills.

Journal: Journal of ethnopharmacology
Published Date: Jun 7, 2025

Abstract

ETHNOPHARMACOLOGICAL RELEVANCE: Angong Niuhuang Pills (AGNHP), a famous Chinese medicine compound preparation, is widely used to treat stroke and other brain disorders. However, owing to the complexity of herbal components and diversity of production processes, quality control is challenging.

Authors

  • Mengyin Tian
    NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China; National Glycoengineering Research Center, Shandong University, Qingdao, Shandong, 266200, China; Key Laboratory of Chemical Biology (Ministry of Education), Shandong University, Jinan, Shandong, 250012, China.
  • Xiaobo Ma
    NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China; National Glycoengineering Research Center, Shandong University, Qingdao, Shandong, 266200, China; Key Laboratory of Chemical Biology (Ministry of Education), Shandong University, Jinan, Shandong, 250012, China.
  • Lei Nie
    NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China.
  • Hengchang Zang
    NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China.

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