Micronutrient supplementation influences the composition and diet-originating function of the gut microbiome in healthy adults.

Journal: Clinical nutrition (Edinburgh, Scotland)
Published Date:

Abstract

BACKGROUND & AIMS: Studies in-vitro and in animals propose that vitamins and minerals can alter the human gut microbiome. Human trials replicating these findings are scarce or used micronutrient supplementation in supraphysiological doses. We explored the effect of multivitamin/multimineral (MVMM) supplementation on the gut microbiome, and how participant's background diet can modify this effect.

Authors

  • Shona Mckirdy
    Human Nutrition, School of Medicine, Dentistry & Nursing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom.
  • Athanasios Koutsos
    Human Nutrition, School of Medicine, Dentistry & Nursing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom.
  • Ben Nichols
    Human Nutrition, School of Medicine, Dentistry & Nursing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom.
  • Maris Anderson
    Human Nutrition, School of Medicine, Dentistry & Nursing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom.
  • Sumet Dhami
    Human Nutrition, School of Medicine, Dentistry & Nursing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom.
  • Chandrama Roy Chowdhury
    Department of Food Science, Czech University of Life Sciences Prague, Prague, Czech Republic.
  • Anna Mascellani Bergo
    Department of Food Science, Czech University of Life Sciences Prague, Prague, Czech Republic.
  • Jaroslav Havlik
    Department of Food Science, Czech University of Life Sciences Prague, Prague, Czech Republic.
  • Konstantinos Gerasimidis
    Human Nutrition, School of Medicine, Dentistry & Nursing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom. Electronic address: Konstantinos.Gerasimidis@glasgow.ac.uk.