Analysis of Multiple Programmed Cell Death Patterns and Functional Validations of Apoptosis-Associated Genes in Lung Adenocarcinoma.

Journal: Annals of surgical oncology
Published Date:

Abstract

BACKGROUND: Lung adenocarcinoma (LUAD) is marked by its considerable aggressiveness and pronounced heterogeneity. Programmed cell death (PCD) plays a pivotal role in the progression of tumors, their aggressive behavior, resistance to treatment, and recurrence of the disease.

Authors

  • Yu Peng
  • Nan Jia
    School of Nursing, Capital Medical University, No. 10, Xi tou tiao, You An Men Wai, Feng tai District, Beijing, 100069 China.
  • Jingyu Wang
    Center of Medical & Health Analysis, School of Public Health, Peking University, Beijing, China.
  • Shilei Dong
    Department of Radiotherapy, Affiliated Hospital of Hebei University, Baoding, China. Electronic address: 15200038090@163.com.
  • Shujun Li
    Department of Thoracic Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China. lishujun2333@163.com.
  • Wei Qin
    School of Life Sciences and Technology, Xidian University, Xi'an, China.
  • Hongyun Shi
    Department of Radiotherapy, Affiliated Hospital of Hebei University, Baoding, China. hyshihbuniversity@163.com.
  • Kuan Liu
    Department of Radiotherapy, Affiliated Hospital of Hebei University, Baoding, China. liukuanhdfs@sina.com.