Serum metabolite biomarkers for the early diagnosis and monitoring of age-related macular degeneration.

Journal: Journal of advanced research
Published Date:

Abstract

INTRODUCTION: Age-related macular degeneration (AMD) is a leading cause of irreversible blindness worldwide, with significant challenges for early diagnosis and treatment.

Authors

  • Shengjie Li
    Department of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan 250014, China.
  • Yichao Qiu
    Department of Clinical Laboratory, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
  • Yingzhu Li
    Department of Clinical Laboratory, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
  • Jianing Wu
    School of Aeronautics and Astronautics, Sun Yat-Sen University, Guangzhou, 510006, P. R. China.
  • Ning Yin
    Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China; National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai 200080, China.
  • Jun Ren
    School of Life Science and Technology, Harbin Institute of Technology, Harbin, 150001, People's Republic of China.
  • Mingxi Shao
    Department of Clinical Laboratory, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
  • Jian Yu
    Key laboratory of Transplantation, Chinese Academy of Medical Sciences, Tianjin, 300192, China; Tianjin Key Laboratory for Organ Transplantation, Tianjin First Center Hospital, Tianjin, 300192, China; Department of Liver Transplantation, Tianjin Medical University First Center Clinical College, Tianjin, 300192, China; Tianjin Key Laboratory of Molecular and Treatment of Liver Cancer, Tianjin First Center Hospital, Tianjin, 300192, China.
  • Yunxiao Song
    Department of Clinical Laboratory, Shanghai Xuhui Central Hospital, Fudan University, Shanghai, China. xzxsh@sina.com.
  • Xinghuai Sun
    Department of Ophthalmology and Visual Science, Eye, Ear, Nose and Throat Hospital, Shanghai Medical College of Fudan University.
  • Shunxiang Gao
    Eye Institute, Eye and ENT Hospital, College of Medicine, Fudan University, Shanghai, China; Shanghai Key Laboratory of Visual Impairment and Restoration, Science and Technology Commission of Shanghai Municipality, Shanghai, China; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China.
  • Wenjun Cao
    Department of Clinical Laboratory, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, China. wgkjyk@aliyun.com.