Artificial neural network-based model enhances risk stratification and reduces non-invasive cardiac stress imaging compared to Diamond-Forrester and Morise risk assessment models: A prospective study.

Journal: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Published Date:

Abstract

BACKGROUND: Coronary artery disease (CAD) accounts for more than half of all cardiovascular events. Stress testing remains the cornerstone for non-invasive assessment of patients with possible or known CAD. Clinical utilization reviews show that most patients presenting for evaluation of stable CAD by stress testing are categorized as low risk prior to the test. Attempts to enhance risk stratification of individuals who are sent for stress testing seem to be more in need today. The present study compares artificial neural networks (ANN)-based prediction models to the other risk models being used in practice (the Diamond-Forrester and the Morise models).

Authors

  • Hussain A Isma'eel
    Division of Cardiology, Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.
  • George E Sakr
    Vascular Medicine Program, American University of Beirut Medical Center, Riad el Solh, PO Box 11-023, Beirut, 11072020, Lebanon. ges07.aub@gmail.com.
  • Mustapha Serhan
    Division of Cardiology, Department of Internal Medicine, American University of Beirut, PO-BOX 11-0236, Riad el Solh, Beirut, 11072020, Lebanon.
  • Nader Lamaa
    Division of Cardiology, Department of Internal Medicine, American University of Beirut, PO-BOX 11-0236, Riad el Solh, Beirut, 11072020, Lebanon.
  • Ayman Hakim
    Division of Cardiology, Department of Internal Medicine, American University of Beirut, PO-BOX 11-0236, Riad el Solh, Beirut, 11072020, Lebanon.
  • Paul C Cremer
    Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Wael A Jaber
    Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA. jaberw@ccf.org.
  • Torkom Garabedian
    Department of Internal Medicine, Saint Elizabeth's Medical Center, Boston, MA, USA.
  • Imad Elhajj
    Vascular Medicine Program, American University of Beirut Medical Center, Beirut, Lebanon.
  • Antoine B Abchee
    Division of Cardiology, Department of Internal Medicine, American University of Beirut, PO-BOX 11-0236, Riad el Solh, Beirut, 11072020, Lebanon.