Feasibility of Automated Propofol Sedation for Transcatheter Aortic Valve Implantation: A Pilot Study.
Journal:
Anesthesia and analgesia
PMID:
28027088
Abstract
BACKGROUND: Recently, several trials have shown that closed-loop sedation is feasible. No study has used automated sedation in extremely frail patients, such as those scheduled for transcatheter aortic valve implantation (TAVI). We developed and tested a novel automated sedation system for this kind of population and surgery. The system integrates a decision support system that detects respiratory and hemodynamic events via smart alarms, which provide pertinent/related clinical suggestions and treatment options. The main objective was the feasibility of closed-loop sedation, defined as successful automated sedation without manual override. Secondary qualitative observations were clinical and controller performance.
Authors
Keywords
Aged
Aged, 80 and over
Anesthesia, Intravenous
Anesthetics, Intravenous
Automation
Clinical Alarms
Consciousness Monitors
Decision Support Systems, Clinical
Elective Surgical Procedures
Equipment Design
Feasibility Studies
Female
Hemodynamics
Humans
Hypnotics and Sedatives
Male
Monitoring, Intraoperative
Pilot Projects
Propofol
Prospective Studies
Respiration
Risk Factors
Robotics
Transcatheter Aortic Valve Replacement
Treatment Outcome