Predicting Response to Repetitive Transcranial Magnetic Stimulation in Patients With Schizophrenia Using Structural Magnetic Resonance Imaging: A Multisite Machine Learning Analysis.

Journal: Schizophrenia bulletin
PMID:

Abstract

BACKGROUND: The variability of responses to plasticity-inducing repetitive transcranial magnetic stimulation (rTMS) challenges its successful application in psychiatric care. No objective means currently exists to individually predict the patients' response to rTMS.

Authors

  • Nikolaos Koutsouleris
    Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
  • Thomas Wobrock
    Department of Psychiatry and Psychotherapy, Georg-August-University Goettingen.
  • Birgit Guse
    Department of Psychiatry and Psychotherapy, Georg-August-University Goettingen.
  • Berthold Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg.
  • Michael Landgrebe
    Department of Psychiatry and Psychotherapy, University of Regensburg.
  • Peter Eichhammer
    Department of Psychiatry and Psychotherapy, University of Regensburg.
  • Elmar Frank
    Department of Psychiatry and Psychotherapy, University of Regensburg.
  • Joachim Cordes
    Department of Psychiatry and Psychotherapy, Heinrich-Heine University, Düsseldorf.
  • Wolfgang Wölwer
    Department of Psychiatry and Psychotherapy, Heinrich-Heine University, Düsseldorf.
  • Francesco Musso
    Department of Psychiatry and Psychotherapy, Heinrich-Heine University, Düsseldorf.
  • Georg Winterer
    Experimental and Clinical Research Center, Charité-University Medicine Berlin, Berlin, Germany. Electronic address: georg.winterer@charite.de.
  • Wolfgang Gaebel
    Department of Psychiatry and Psychotherapy, Heinrich-Heine University, Düsseldorf.
  • Göran Hajak
    European Clinical Research Infrastructure Network (ECRIN), Düsseldorf, Germany.
  • Christian Ohmann
    Coordination Centre for Clinical Trials, Heinrich-Heine University, Düsseldorf.
  • Pablo E Verde
    Coordination Centre for Clinical Trials, Heinrich-Heine University, Düsseldorf.
  • Marcella Rietschel
    Department of Genetic Epidemiology in Psychiatry, Institute of Central Mental Health, Medical Faculty Mannheim, University of Heidelberg.
  • Raees Ahmed
    Referat Klinische Studien Management, Georg-August-University Goettingen.
  • William G Honer
    Institute of Mental Health, The University of British Columbia, Vancouver, Canada.
  • Dominic Dwyer
    Department of Psychiatry and Psychotherapy, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich.
  • Farhad Ghaseminejad
    Institute of Mental Health, The University of British Columbia, Vancouver, Canada.
  • Peter Dechent
    Department of Cognitive Neurology, Georg-August-University Goettingen.
  • Berend Malchow
    Department of Psychiatry and Psychotherapy, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich.
  • Peter M Kreuzer
    Department of Psychiatry and Psychotherapy, University of Regensburg.
  • Tim B Poeppl
    Department of Psychiatry and Psychotherapy, University of Regensburg.
  • Thomas Schneider-Axmann
    Department of Psychiatry and Psychotherapy, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich.
  • Peter Falkai
    Department of Psychiatry and Psychotherapy, Ludwig-Maximilian-University, Munich, Germany;
  • Alkomiet Hasan
    Department of Psychiatry and Psychotherapy, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich.