Radiomics-Based Intracranial Thrombus Features on CT and CTA Predict Recanalization with Intravenous Alteplase in Patients with Acute Ischemic Stroke.

Journal: AJNR. American journal of neuroradiology
Published Date: Jan 1, 2019

Abstract

BACKGROUND AND PURPOSE: Thrombus characteristics identified on non-contrast CT (NCCT) are potentially associated with recanalization with intravenous (IV) alteplase in patients with acute ischemic stroke (AIS). Our aim was to determine the best radiomics-based features of thrombus on NCCT and CT angiography associated with recanalization with IV alteplase in AIS patients and proximal intracranial thrombi.

Authors

  • W Qiu
    From the Calgary Stroke Program (H.K., W.Q., M.N., D.C., N.M., M.G., M.D.H., A.M.D., B.K.M.) qiu.wu.ch@gmail.com.
  • H Kuang
    From the Calgary Stroke Program (H.K., W.Q., M.N., D.C., N.M., M.G., M.D.H., A.M.D., B.K.M.).
  • J Nair
    From the Departments of Clinical Neurosciences (W.Q., H.K., J.N., Z.A. M.N., C.M., A.T.W., B.M., M.G., M.D.H., A.M.D., B.K.M.).
  • Z Assis
    From the Departments of Clinical Neurosciences (W.Q., H.K., J.N., Z.A. M.N., C.M., A.T.W., B.M., M.G., M.D.H., A.M.D., B.K.M.).
  • M Najm
    From the Calgary Stroke Program (H.K., W.Q., M.N., D.C., N.M., M.G., M.D.H., A.M.D., B.K.M.).
  • C McDougall
    From the Departments of Clinical Neurosciences (W.Q., H.K., J.N., Z.A. M.N., C.M., A.T.W., B.M., M.G., M.D.H., A.M.D., B.K.M.).
  • B McDougall
    From the Departments of Clinical Neurosciences (W.Q., H.K., J.N., Z.A. M.N., C.M., A.T.W., B.M., M.G., M.D.H., A.M.D., B.K.M.).
  • K Chung
    Calgary Stroke Program, Mechanical and Manufacturing Engineering (K.C.).
  • A T Wilson
    From the Departments of Clinical Neurosciences (W.Q., H.K., J.N., Z.A. M.N., C.M., A.T.W., B.M., M.G., M.D.H., A.M.D., B.K.M.).
  • M Goyal
    From the Calgary Stroke Program (H.K., W.Q., M.N., D.C., N.M., M.G., M.D.H., A.M.D., B.K.M.).
  • M D Hill
    From the Calgary Stroke Program (H.K., W.Q., M.N., D.C., N.M., M.G., M.D.H., A.M.D., B.K.M.).
  • A M Demchuk
    From the Calgary Stroke Program (H.K., W.Q., M.N., D.C., N.M., M.G., M.D.H., A.M.D., B.K.M.).
  • B K Menon
    From the Calgary Stroke Program (H.K., W.Q., M.N., D.C., N.M., M.G., M.D.H., A.M.D., B.K.M.).

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