Machine Learning Prediction of Response to Cardiac Resynchronization Therapy: Improvement Versus Current Guidelines.

Journal: Circulation. Arrhythmia and electrophysiology
PMID: 31216884

Abstract

BACKGROUND: Cardiac resynchronization therapy (CRT) has significant nonresponse rates. We assessed whether machine learning (ML) could predict CRT response beyond current guidelines.

Authors

  • Albert K Feeny
    Cleveland Clinic Lerner College of Medicine (A.K.F., M.A.L.), Case Western Reserve University, OH.
  • John Rickard
    Department of Cardiovascular Medicine, Heart and Vascular Institute (J.R., D.P., S.T., K.M.T., N.V., M.J.N., E.Z.G., R.A.G., M.K.C.), Cleveland Clinic, OH.
  • Divyang Patel
    Department of Cardiovascular Medicine, Heart and Vascular Institute (J.R., D.P., S.T., K.M.T., N.V., M.J.N., E.Z.G., R.A.G., M.K.C.), Cleveland Clinic, OH.
  • Saleem Toro
    Department of Cardiovascular Medicine, Heart and Vascular Institute (J.R., D.P., S.T., K.M.T., N.V., M.J.N., E.Z.G., R.A.G., M.K.C.), Cleveland Clinic, OH.
  • Kevin M Trulock
    Department of Cardiovascular Medicine, Heart and Vascular Institute (J.R., D.P., S.T., K.M.T., N.V., M.J.N., E.Z.G., R.A.G., M.K.C.), Cleveland Clinic, OH.
  • Carolyn J Park
    Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD (C.J.P., S.S., D.D.S.).
  • Michael A LaBarbera
    Cleveland Clinic Lerner College of Medicine (A.K.F., M.A.L.), Case Western Reserve University, OH.
  • Niraj Varma
    Department of Cardiovascular Medicine, Heart and Vascular Institute (J.R., D.P., S.T., K.M.T., N.V., M.J.N., E.Z.G., R.A.G., M.K.C.), Cleveland Clinic, OH.
  • Mark J Niebauer
    Department of Cardiovascular Medicine, Heart and Vascular Institute (J.R., D.P., S.T., K.M.T., N.V., M.J.N., E.Z.G., R.A.G., M.K.C.), Cleveland Clinic, OH.
  • Sunil Sinha
    Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD (C.J.P., S.S., D.D.S.).
  • Eiran Z Gorodeski
    Department of Cardiovascular Medicine, Heart and Vascular Institute (J.R., D.P., S.T., K.M.T., N.V., M.J.N., E.Z.G., R.A.G., M.K.C.), Cleveland Clinic, OH.
  • Richard A Grimm
    Department of Cardiovascular Medicine, Heart and Vascular Institute (J.R., D.P., S.T., K.M.T., N.V., M.J.N., E.Z.G., R.A.G., M.K.C.), Cleveland Clinic, OH.
  • Xinge Ji
    Department of Quantitative Health Sciences, Lerner Research Institute (X.J., J.B.), Cleveland Clinic, OH.
  • John Barnard
    Department of Quantitative Health Sciences, Lerner Research Institute (X.J., J.B.), Cleveland Clinic, OH.
  • Anant Madabhushi
    Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio.
  • David D Spragg
    Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD (C.J.P., S.S., D.D.S.).
  • Mina K Chung
    Department of Cardiovascular Medicine, Heart and Vascular Institute (J.R., D.P., S.T., K.M.T., N.V., M.J.N., E.Z.G., R.A.G., M.K.C.), Cleveland Clinic, OH.

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