Artificial neural networks allow response prediction in squamous cell carcinoma of the scalp treated with radiotherapy.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV
PMID: 31968143

Abstract

BACKGROUND: Epithelial neoplasms of the scalp account for approximately 2% of all skin cancers and for about 10-20% of the tumours affecting the head and neck area. Radiotherapy is suggested for localized cutaneous squamous cell carcinomas (cSCC) without lymph node involvement, multiple or extensive lesions, for patients refusing surgery, for patients with a poor general medical status, as adjuvant for incompletely excised lesions and/or as a palliative treatment. To date, prognostic risk factors in scalp cSCC patients are poorly characterized.

Authors

  • G Damiani
    Clinical Dermatology, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
  • E Grossi
    Centro Diagnostico Italiano, Milano, Italy.
  • E Berti
    Phototherapy Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
  • R R Z Conic
    Department of Dermatology, Case Western Reserve University, Cleveland, OH, USA.
  • U Radhakrishna
    Department of Obstetrics and Gynecology, Oakland University William Beaumont School of Medicine, Royal Oak, MI, USA.
  • A Pacifico
    Clinical Dermatology Department, IRCCS S. Gallicano Dermatological Institute, Rome, Italy.
  • N L Bragazzi
    School of Public Health, Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
  • R Piccinno
    Phototherapy Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
  • D Linder
    Ben Gurion University of the Negev, Beer Sheva, Israel.

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