Development and validation of machine learning prediction model based on computed tomography angiography-derived hemodynamics for rupture status of intracranial aneurysms: a Chinese multicenter study.

Journal: European radiology
Published Date:

Abstract

OBJECTIVES: To build models based on conventional logistic regression (LR) and machine learning (ML) algorithms combining clinical, morphological, and hemodynamic information to predict individual rupture status of unruptured intracranial aneurysms (UIAs), afterwards tested in internal and external validation datasets.

Authors

  • Guozhong Chen
    Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, Jiangsu, China.
  • Mengjie Lu
    Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, Jiangsu, China.
  • Zhao Shi
    Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, Jiangsu, China.
  • Shuang Xia
    Department of Radiology, Tianjin First Central Hospital, Tianjin, China.
  • Yuan Ren
  • Zhen Liu
    School of Pharmacy, Fudan University, PR China; Analytical Service Unit, WuXi AppTec (Shanghai) Co., Ltd, Shanghai, 200131, PR China.
  • Xiuxian Liu
    School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.
  • Zhiyong Li
    School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.
  • Li Mao
    Deepwise AI Lab, Deepwise Inc, No.8 Haidian avenue, Sinosteel International Plaza, Beijing, 100080, China.
  • Xiu Li Li
    Deepwise AI Lab, Beijing, 100089, China.
  • Bo Zhang
    Department of Clinical Pharmacology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, PR China.
  • Long Jiang Zhang
  • Guang Ming Lu