Unsupervised Cluster Analysis of Patients With Aortic Stenosis Reveals Distinct Population With Different Phenotypes and Outcomes.

Journal: Circulation. Cardiovascular imaging
PMID:

Abstract

BACKGROUND: There is a lack of studies investigating the heterogeneity of patients with aortic stenosis (AS). We explored whether cluster analysis identifies distinct subgroups with different prognostic significances in AS.

Authors

  • Soongu Kwak
    Department of Internal Medicine (S.K., S.Y., J.-B.P., H.-K.K., Y.-J.K., D.-W.S., S.-P.L.), Seoul National University Hospital.
  • Yunhwan Lee
    Department of Public Health Sciences, Seoul National University (Y.L., S.W.).
  • Taehoon Ko
    Office of Hospital Information, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, South Korea.
  • Seokhun Yang
    Department of Internal Medicine (S.K., S.Y., J.-B.P., H.-K.K., Y.-J.K., D.-W.S., S.-P.L.), Seoul National University Hospital.
  • In-Chang Hwang
    Department of Internal Medicine, Seoul National University Bundang Hospital, Gyeonggi-do (I.-C.H., Y.E.Y., G.-Y.C.).
  • Jun-Bean Park
    Department of Internal Medicine (S.K., S.Y., J.-B.P., H.-K.K., Y.-J.K., D.-W.S., S.-P.L.), Seoul National University Hospital.
  • Yeonyee E Yoon
    Department of Internal Medicine, Seoul National University Bundang Hospital, Gyeonggi-do (I.-C.H., Y.E.Y., G.-Y.C.).
  • Hack-Lyoung Kim
    Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, South Korea (H.-L.K.).
  • Hyung-Kwan Kim
    Department of Internal Medicine (S.K., S.Y., J.-B.P., H.-K.K., Y.-J.K., D.-W.S., S.-P.L.), Seoul National University Hospital.
  • Yong-Jin Kim
    Seoul National University Hospital, Seoul, South Korea.
  • Goo-Yeong Cho
    Department of Internal Medicine, Seoul National University Bundang Hospital, Gyeonggi-do (I.-C.H., Y.E.Y., G.-Y.C.).
  • Dae-Won Sohn
    Department of Internal Medicine (S.K., S.Y., J.-B.P., H.-K.K., Y.-J.K., D.-W.S., S.-P.L.), Seoul National University Hospital.
  • Sungho Won
    Department of Public Health Sciences, Seoul National University (Y.L., S.W.).
  • Seung-Pyo Lee
    Department of Oral Anatomy, Dental Research Institute, School of Dentistry Seoul National University, Seoul, South Korea.