HCV nonstructural protein 4 is associated with aggressiveness features of breast cancer.

Journal: Breast cancer (Tokyo, Japan)
PMID: 29285674

Abstract

BACKGROUND: Hepatitis C virus (HCV) has the lymphotropic feature that is supposed to be the reason of related extrahepatic manifestation. HCV viral oncoproteins may participate in the regulation of some gene expression that has been implicated in tumorigenesis. Our aim is to evaluate the HCV-NS4 circulating levels in breast cancer (BC) and to investigate its relation with BC tumor aggressiveness.

Authors

  • Abdelfattah M Attallah
    Research and Development Department, Biotechnology Research Center, P.O. Box (14), 23 July St., Industrial Zone, New Damietta, 34517, Egypt. amattallah@hotmail.com.
  • Mohamed El-Far
    Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
  • Mohamed A Abdelrazek
    Research and Development Department, Biotechnology Research Center, P.O. Box (14), 23 July St., Industrial Zone, New Damietta, 34517, Egypt.
  • Mohamed M Omran
    Chemistry Department, Faculty of Science, Helwan University, Cairo, Egypt.
  • Ashraf Z Mahmoud
    Molecular Biology Division, Mansoura University, Mansoura, Egypt.
  • Hager S Khalifa
    Research and Development Department, Biotechnology Research Center, P.O. Box (14), 23 July St., Industrial Zone, New Damietta, 34517, Egypt.
  • Mohamed M Ahmed
    Research and Development Department, Biotechnology Research Center, P.O. Box (14), 23 July St., Industrial Zone, New Damietta, 34517, Egypt.
  • Ibrahim El-Dosoky
    Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

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