AIMC Topic: Mucin-1

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Antifouling Capture and Dual-Targeting Recognition-Induced Signal Amplification for Triple-Mode Detection and Identification of Circulating Tumor Cells.

Analytical chemistry Jun 12, 2025
Circulating tumor cells (CTCs) are promising biomarkers for cancer diagnosis, while detecting CTCs in clinical samples is still challenging due to the scarcity and heterogeneity of CTCs. Herein, a triple-mode sensing platform based on an antifouling ...
Humans Aptamers, Nucleotide Biosensing Techniques G-Quadruplexes Mucin-1 Biofouling Neoplastic Cells, Circulating HeLa Cells Magnetite Nanoparticles
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Enhancing electrochemical detection through machine learning-driven prediction for canine mammary tumor biomarker with green silver nanoparticles.

Analytical and bioanalytical chemistry Jul 20, 2024
This study developed an innovative biosensor strategy for the sensitive and selective detection of canine mammary tumor biomarkers, cancer antigen 15-3 (CA 15-3) and mucin 1 (MUC-1), integrating green silver nanoparticles (GAgNPs) with machine learni...
Machine Learning Metal Nanoparticles Mucin-1 Limit of Detection Mammary Neoplasms, Animal Dogs Dog Diseases Female Silver Biosensing Techniques Biomarkers, Tumor Electrochemical Techniques Animals
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Molecular imaging and deep learning analysis of uMUC1 expression in response to chemotherapy in an orthotopic model of ovarian cancer.

Scientific reports Sep 10, 2020
Artificial Intelligence (AI) algorithms including deep learning have recently demonstrated remarkable progress in image-recognition tasks. Here, we utilized AI for monitoring the expression of underglycosylated mucin 1 (uMUC1) tumor antigen, a biomar...
Apoptosis Ovarian Neoplasms Docetaxel Cell Proliferation Mice, Nude Mucin-1 Tumor Cells, Cultured Molecular Imaging Xenograft Model Antitumor Assays Female Animals Deep Learning Mice Antineoplastic Agents Humans Artificial Intelligence
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Function2Form Bridge-Toward synthetic protein holistic performance prediction.

Proteins Oct 29, 2019
Protein engineering and synthetic biology stand to benefit immensely from recent advances in silico tools for structural and functional analyses of proteins. In the context of designing novel proteins, current in silico tools inform the user on indiv...
Coagulase Mucin-1 Protein Engineering Staphylococcus aureus Models, Statistical Antibodies Synthetic Biology Humans Structure-Activity Relationship Machine Learning
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8-Hydroxy-2'-deoxyguanosine as a Discriminatory Biomarker for Early Detection of Breast Cancer.

Clinical breast cancer Dec 21, 2018
BACKGROUND: Breast cancer (BC) is one of the most prevalent and reported cancers among Saudi women. Detection of BC in the early invasive stage (stages I, II) has an advantage in treating patients over detection in the late invasive stage (stages III...
Risk Case-Control Studies Postmenopause GPI-Linked Proteins Early Detection of Cancer Sensitivity and Specificity Mucin-1 Humans Carcinoembryonic Antigen Breast Neoplasms 8-Hydroxy-2'-Deoxyguanosine Biomarkers, Tumor Female
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HCV nonstructural protein 4 is associated with aggressiveness features of breast cancer.

Breast cancer (Tokyo, Japan) Dec 28, 2017
BACKGROUND: Hepatitis C virus (HCV) has the lymphotropic feature that is supposed to be the reason of related extrahepatic manifestation. HCV viral oncoproteins may participate in the regulation of some gene expression that has been implicated in tum...
Neoplasm Staging Neoplasm Grading Hepacivirus Hepatitis C Fibronectins Enzyme-Linked Immunosorbent Assay Carcinogenesis Egypt Incidence Humans Gene Expression Regulation, Neoplastic Hepatitis C Antibodies Breast Neoplasms Female Viral Nonstructural Proteins Aged Middle Aged Mucin-1 Adult Disease Progression
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