Post prostatectomy outcomes of patients with high-risk prostate cancer treated with neoadjuvant androgen blockade.

Journal: Prostate cancer and prostatic diseases
PMID:

Abstract

BACKGROUND: Patients with high-risk prostate cancer have an increased likelihood of experiencing a relapse following radical prostatectomy (RP). We previously conducted three neoadjuvant androgen-deprivation therapy (ADT) trials prior to RP in unfavorable intermediate and high-risk disease.

Authors

  • Rana R Mckay
    University of California San Diego, San Diego, CA, USA.
  • Bruce Montgomery
    Department of Medicine, Division of Oncology, University of Washington, Seattle, WA, USA.
  • Wanling Xie
    Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Zhenwei Zhang
    Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Glenn J Bubley
    Department of Medicine, Division of Hematology/Oncology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • David W Lin
    Department of Urology, University of Washington, Seattle, WA, USA.
  • Mark A Preston
    Department of Surgery, Division of Urology, Dana Farber/Brigham and Women's Cancer Center, Boston, MA, USA.
  • Quoc-Dien Trinh
    Department of Surgery, Division of Urology, Dana Farber/Brigham and Women's Cancer Center, Boston, MA, USA.
  • Peter Chang
    Department of Urology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Andrew A Wagner
    Department of Urology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Elahe A Mostaghel
    Department of Medicine, Division of Oncology, University of Washington, Seattle, WA, USA.
  • Philip W Kantoff
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Peter S Nelson
    Department of Medicine, Division of Oncology, University of Washington, Seattle, WA, USA.
  • Adam S Kibel
    Department of Surgery, Division of Urology, Dana Farber/Brigham and Women's Cancer Center, Boston, MA, USA.
  • Mary-Ellen Taplin
    Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. Mary_Taplin@DFCI.harvard.edu.