Interpretable machine learning model integrating clinical and elastosonographic features to detect renal fibrosis in Asian patients with chronic kidney disease.

Journal: Journal of nephrology
PMID:

Abstract

BACKGROUND: Non-invasive renal fibrosis assessment is critical for tailoring personalized decision-making and managing follow-up in patients with chronic kidney disease (CKD). We aimed to exploit machine learning algorithms using clinical and elastosonographic features to distinguish moderate-severe fibrosis from mild fibrosis among CKD patients.

Authors

  • Ziman Chen
    Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong. chenzm27@mail3.sysu.edu.cn.
  • Yingli Wang
    Ultrasound Department, EDAN Instruments, Inc., Shenzhen, China.
  • Michael Tin Cheung Ying
    Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong. michael.ying@polyu.edu.hk.
  • Zhongzhen Su
    Department of Ultrasound, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.