AI Medical Compendium Journal:
BioTechniques

Showing 1 to 10 of 11 articles

An automatic classification method of testicular histopathology based on SC-YOLO framework.

BioTechniques
The pathological diagnosis and treatment of azoospermia depend on precise identification of spermatogenic cells. Traditional methods are time-consuming and highly subjective due to complexity of Johnsen score, posing challenges for accurately diagnos...

The environmental impact of AI in the lab: a double-edged sword?

BioTechniques
Computational tools, particularly AI, are becoming more ubiquitous in scientific research; but what impact do they have on the environment?[Formula: see text].

Artificial intelligence: help or hindrance in solving the reproducibility crisis?

BioTechniques
Science is in the midst of a reproducibility crisis and the integration of artificial intelligence into scientific research has only compounded the problem; yet could the technology hold the solution to its own problems?[Formula: see text].

The dynamic duo: cryo-EM teams up with machine learning to visualize biomolecules in motion.

BioTechniques
Cryo-EM has been a key technique in our understanding of biomolecular structures. Now, machine learning techniques are being used to put these structures in motion, revealing dynamic interactions and processes happening on a molecular and cellular le...

Comparing robotic and manual injection methods in zebrafish embryos for high-throughput RNA silencing using CRISPR-RfxCas13d.

BioTechniques
In this study, the authors compared the efficiency of automated robotic and manual injection methods for the CRISPR-RfxCas13d (CasRx) system for mRNA knockdown and Cas9-mediated DNA targeting in zebrafish embryos. They targeted the no tail () gene as...

Predicting molecular docking of per- and polyfluoroalkyl substances to blood protein using generative artificial intelligence algorithm DiffDock.

BioTechniques
This study computationally evaluates the molecular docking affinity of various perfluoroalkyl and polyfluoroalkyl substances (PFAs) towards blood proteins using a generative machine-learning algorithm, DiffDock, specialized in protein-ligand blind-do...

I know what you're thinking; can neuroimaging truly reveal our innermost thoughts?

BioTechniques
[Formula: see text] Advances in neuroimaging, combined with developments in artificial intelligence software, have allowed researchers to noninvasively decode the brain and 'read the mind'.

Has DeepMind's AlphaFold solved the protein folding problem?

BioTechniques
DeepMind released AlphaFold 2.0 in 2020, an artificial intelligence model to predict the structure of proteins, which could mean that proteins can be characterized without the need for tedious and costly lab analysis.

The path to solving the protein folding problem.

BioTechniques
[Formula: see text] With advances in imaging technologies and the development of artificial intelligence-based predictive software, has the protein folding problem finally been solved?