Current opinion in biotechnology
Jan 12, 2023
Genomics and deep learning are a natural match since both are data-driven fields. Regulatory genomics refers to functional noncoding DNA regulating gene expression. In recent years, deep learning applications on regulatory genomics have achieved rema...
Current opinion in biotechnology
Jan 3, 2023
Self-driving labs (SDLs) combine fully automated experiments with artificial intelligence (AI) that decides the next set of experiments. Taken to their ultimate expression, SDLs could usher a new paradigm of scientific research, where the world is pr...
Current opinion in biotechnology
Dec 2, 2022
Predicting phenotype with genomic and environmental information is critically needed and challenging. Machine learning methods have emerged as powerful tools to make accurate predictions from large and complex biological data. Here, we review the pro...
Current opinion in biotechnology
Sep 8, 2022
Current biomanufacturing facilities are mainly built for batch or fed-batch operations, which are subject to low productivities and do not achieve the great bioconversion potential of the rewired cells generated via modern biotechnology. Continuous b...
Current opinion in biotechnology
Apr 29, 2022
Recent Industry 4.0 advancements are making available massive amounts of data for the development of innovative BioTech solutions. However, several challenges need to be overcome to correctly use data and novel, non-pharma technologies to greatly spe...
Current opinion in biotechnology
Apr 9, 2022
Machine learning (ML) is revolutionizing our ability to understand and predict the complex relationships between protein sequence, structure, and function. Predictive sequence-function models are enabling protein engineers to efficiently search the s...
Current opinion in biotechnology
Apr 7, 2022
Iterative design-build-test-learn (DBTL) cycles are routinely performed during microbial strain development. This useful approach integrates computational strain design, genetic engineering, fermentation testing, and omics analysis to reveal and reso...
Current opinion in biotechnology
Nov 1, 2021
Development of neural interface and brain-machine interface (BMI) systems enables the treatment of neurological disorders including cognitive, sensory, and motor dysfunctions. While neural interfaces have steadily decreased in form factor, recent dev...
Current opinion in biotechnology
Aug 3, 2021
Metabolic engineering for developing industrial strains capable of overproducing bioproducts requires good understanding of cellular metabolism, including metabolic reactions and enzymes. However, metabolic pathways and enzymes involved are still unk...
Current opinion in biotechnology
Oct 7, 2020
Modern agriculture and food production systems are facing increasing pressures from climate change, land and water availability, and, more recently, a pandemic. These factors are threatening the environmental and economic sustainability of current an...