AI Medical Compendium Journal:
Journal of the Royal Society, Interface

Showing 1 to 10 of 82 articles

Scientific hypothesis generation by large language models: laboratory validation in breast cancer treatment.

Journal of the Royal Society, Interface
Large language models (LLMs) have transformed artificial intelligence (AI) and achieved breakthrough performance on a wide range of tasks. In science, the most interesting application of LLMs is for hypothesis formation. A feature of LLMs, which resu...

Exploring the evolutionary adaptations of the unique seahorse tail's muscle architecture through modelling and robotic prototyping.

Journal of the Royal Society, Interface
Seahorses possess a unique tail muscle architecture that enables efficient grasping and anchoring onto objects. This prehensile ability is crucial for their survival, as it allows them to resist currents, cling to mates during reproduction and remain...

A systematic evaluation of the language-of-viral-escape model using multiple machine learning frameworks.

Journal of the Royal Society, Interface
Predicting the evolutionary patterns of emerging and endemic viruses is key for mitigating their spread. In particular, it is critical to rapidly identify mutations with the potential for immune escape or increased disease burden. Knowing which circu...

Emerging frontiers in protein structure prediction following the AlphaFold revolution.

Journal of the Royal Society, Interface
Models of protein structures enable molecular understanding of biological processes. Current protein structure prediction tools lie at the interface of biology, chemistry and computer science. Millions of protein structure models have been generated ...

Machine learning-based optimal design of fibrillar adhesives.

Journal of the Royal Society, Interface
Fibrillar adhesion, observed in animals like beetles, spiders and geckos, relies on nanoscopic or microscopic fibrils to enhance surface adhesion via 'contact splitting'. This concept has inspired engineering applications across robotics, transportat...

Upstroke wing clapping in bats and bat-inspired robots offers efficient lift generation.

Journal of the Royal Society, Interface
Wing articulation is critical for the efficient flight of bird- and bat-sized animals. Inspired by the flight of , the lesser short-nosed fruit bat, we built a two-degree-of-freedom flapping wing platform with variable wing folding capability. In the...

Jointed tails enhance control of three-dimensional body rotation.

Journal of the Royal Society, Interface
Tails used as inertial appendages induce body rotations of animals and robots-a phenomenon that is governed largely by the ratio of the body and tail moments of inertia. However, vertebrate tails have more degrees of freedom (e.g. number of joints an...

I2Bot: an open-source tool for multi-modal and embodied simulation of insect navigation.

Journal of the Royal Society, Interface
Achieving a comprehensive understanding of animal intelligence demands an integrative approach that acknowledges the interplay between an organism's brain, body and environment. Insects, despite their limited computational resources, demonstrate rema...

Autonomous learning of generative models with chemical reaction network ensembles.

Journal of the Royal Society, Interface
Can a micron-sized sack of interacting molecules autonomously learn an internal model of a complex and fluctuating environment? We draw insights from control theory, machine learning theory, chemical reaction network theory and statistical physics to...

Cooperative control of environmental extremes by artificial intelligent agents.

Journal of the Royal Society, Interface
Humans have been able to tackle biosphere complexities by acting as ecosystem engineers, profoundly changing the flows of matter, energy and information. This includes major innovations that allowed to reduce and control the impact of extreme events....