AI Medical Compendium Journal:
The journal of physical chemistry. B

Showing 21 to 30 of 48 articles

Employing Artificial Neural Networks to Identify Reaction Coordinates and Pathways for Self-Assembly.

The journal of physical chemistry. B
Capturing the autonomous self-assembly of molecular building blocks in computer simulations is a persistent challenge, requiring to model complex interactions and to access long time scales. Advanced sampling methods allow to bridge these time scales...

Prediction of Self-Diffusion in Binary Fluid Mixtures Using Artificial Neural Networks.

The journal of physical chemistry. B
Artificial neural networks (ANNs) were developed to accurately predict the self-diffusion constants for individual components in binary fluid mixtures. The ANNs were tested on an experimental database of 4328 self-diffusion constants from 131 mixture...

When Bubbles Are Not Spherical: Artificial Intelligence Analysis of Ultrasonic Cavitation Bubbles in Solutions of Varying Concentrations.

The journal of physical chemistry. B
Ultrasonic irradiation of liquids, such as water-alcohol solutions, results in cavitation or the formation of small bubbles. Cavitation bubbles are generated in real solutions without the use of optical traps making our system as close to real condit...

Atomistic Simulations for Reactions and Vibrational Spectroscopy in the Era of Machine Learning─

The journal of physical chemistry. B
Atomistic simulations using accurate energy functions can provide molecular-level insight into functional motions of molecules in the gas and in the condensed phase. This Perspective delineates the present status of the field from the efforts of othe...

Residue-Frustration-Based Prediction of Protein-Protein Interactions Using Machine Learning.

The journal of physical chemistry. B
The study of protein-protein interactions (PPIs) is important in understanding the function of proteins. However, it is still a challenge to investigate the transient protein-protein interaction by experiments. Hence, the computational prediction for...

Charge-Transfer Landscape Manifesting the Structure-Rate Relationship in the Condensed Phase Machine Learning.

The journal of physical chemistry. B
In this work, we develop a machine learning (ML) strategy to map the molecular structure to condensed phase charge-transfer (CT) properties including CT rate constants, energy levels, electronic couplings, energy gaps, reorganization energies, and re...

3D-Scaffold: A Deep Learning Framework to Generate 3D Coordinates of Drug-like Molecules with Desired Scaffolds.

The journal of physical chemistry. B
The prerequisite of therapeutic drug design and discovery is to identify novel molecules and developing lead candidates with desired biophysical and biochemical properties. Deep generative models have demonstrated their ability to find such molecules...

SCONES: Self-Consistent Neural Network for Protein Stability Prediction Upon Mutation.

The journal of physical chemistry. B
Engineering proteins to have desired properties by mutating amino acids at specific sites is commonplace. Such engineered proteins must be stable to function. Experimental methods used to determine stability at throughputs required to scan the protei...

Using Neural Network Force Fields to Ascertain the Quality of Simulations of Liquid Water.

The journal of physical chemistry. B
Accurately simulating the properties of bulk water, despite the apparent simplicity of the molecule, is still a challenge. In order to fully understand and reproduce its complex phase diagram, it is necessary to perform simulations at the level, inc...

Impedance Spectroscopy Dynamics of Biological Neural Elements: From Memristors to Neurons and Synapses.

The journal of physical chemistry. B
Understanding the operation of neurons and synapses is essential to reproducing biological computation. Building artificial neuromorphic networks opens the door to a new generation of faster and low-energy-consuming electronic circuits for computatio...