The complexity and potency of the illicit opioid supply in North America has become increasingly concerning for people who use drugs. Drug checking efforts aim to keep up with the evolving psychoactive components present in the illicit drug supply. W...
Combined use of opioids and other pharmacological therapies used for pain management, such as non-steroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, gabapentinoids, and/or skeletal muscle relaxants (SMRs), in older adult cancer survivors ca...
BACKGROUND: Opioid overuse is a costly and significant problem in the United States. Medical specialties including surgery are a contributor to opioid prescriptions while having few clear prescribing guidelines. Machine learning predictive tools can ...
BACKGROUND: Opioid overdose is a global public health emergency, with the United States experiencing high rates of morbidity and mortality due to prescription and illicit opioid use. Traditional public health monitoring systems often fail to provide ...
The aim of this study was to develop and evaluate a liposomal formulation of fentanyl to improve its analgesic efficacy and safety profile in anesthesia, using artificial intelligence (AI) techniques to characterize and optimize the formulation. The ...
BACKGROUND: The opioid crisis in the United States is a complex issue with interconnected factors that lead to opioid misuse and opioid-involved mortality. This study assessed the relative importance of different risk factor domains in predicting fat...
British journal of hospital medicine (London, England : 2005)
Jul 4, 2025
The opioid crisis presents a significant burden to patients and healthcare systems. Orthopaedic surgery involves treating patients with significant pain demands, therefore opioid stewardship in this specialty is an important area in targeting the opi...
BACKGROUND: The opioid crisis poses a significant health challenge in the United States, with increasing overdoses and death rates due to opioids mixed with other illicit substances. Various strategies have been developed by federal and local governm...
The opioid overdose epidemic has rapidly expanded in North America, with rates accelerating during the COVID-19 pandemic. No existing study has demonstrated prospective opioid overdose at a population level. This study aimed to develop and validate a...
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