AIMC Topic: Anhydrides

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Design, preparation and characterization of pH-responsive prodrug micelles with hydrolyzable anhydride linkages for controlled drug delivery.

Journal of colloid and interface science Dec 31, 2016
We report a new prodrug micelle-based approach in which a model hydrophobic non-steroidal anti-inflammatory drug (NSAID), ibuprofen (Ibu), is tethered to amphiphilic methoxy polyethylene glycol-polypropylene fumarate (mPEG-PPF) diblock copolymer via ...
Humans Animals Nanoparticles Cell Line Cell Survival Drug Carriers Anti-Inflammatory Agents, Non-Steroidal Rabbits Hydrogen-Ion Concentration Polyethylene Glycols Hydrolysis Solubility Drug Liberation Micelles Prodrugs HeLa Cells Hydrophobic and Hydrophilic Interactions Polypropylenes Surface Properties Ibuprofen Anhydrides Fumarates
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