AIMC Topic: Antibody Affinity

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Antibody design using deep learning: from sequence and structure design to affinity maturation.

Briefings in bioinformatics
Deep learning has achieved impressive results in various fields such as computer vision and natural language processing, making it a powerful tool in biology. Its applications now encompass cellular image classification, genomic studies and drug disc...

AttABseq: an attention-based deep learning prediction method for antigen-antibody binding affinity changes based on protein sequences.

Briefings in bioinformatics
The optimization of therapeutic antibodies through traditional techniques, such as candidate screening via hybridoma or phage display, is resource-intensive and time-consuming. In recent years, computational and artificial intelligence-based methods ...

Cytomegalovirus Immunoglobulin G Avidity Index among Blood Donors in Alexandria, Egypt.

Central European journal of public health
BACKGROUND AND AIM: Transfusion transmitted diseases (TTD) are a major challenge to transfusion services all over the world. Cytomegalovirus (CMV) is considered one of the main viruses associated with blood transfusion. As CMV screening is not includ...