AIMC Topic: Antimicrobial Cationic Peptides

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Recent Progress in Machine Learning-based Prediction of Peptide Activity for Drug Discovery.

Current topics in medicinal chemistry Jan 1, 2019
Over the past decades, peptide as a therapeutic candidate has received increasing attention in drug discovery, especially for antimicrobial peptides (AMPs), anticancer peptides (ACPs) and antiinflammatory peptides (AIPs). It is considered that the pe...
Humans Machine Learning Anti-Infective Agents Neoplasms Peptides Drug Discovery Antineoplastic Agents Inflammation Antimicrobial Cationic Peptides
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Improving Recognition of Antimicrobial Peptides and Target Selectivity through Machine Learning and Genetic Programming.

IEEE/ACM transactions on computational biology and bioinformatics Jan 1, 2017
Growing bacterial resistance to antibiotics is spurring research on utilizing naturally-occurring antimicrobial peptides (AMPs) as templates for novel drug design. While experimentalists mainly focus on systematic point mutations to measure the effec...
Neural Networks, Computer Machine Learning Algorithms Drug Design Computational Biology Decision Trees Antimicrobial Cationic Peptides Gram-Negative Bacteria Gram-Positive Bacteria Genetic Engineering
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[Process Optimization of PEGylating Fused Protein of LL-37 and Interferon-α2a].

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi Dec 1, 2015
PEGylating is an effective way for prolonging the half-time period and decreasing the immunogenicity of protein drugs. With experiments of single factor, it was proved that the optimal processes for PEGylating the fused protein of LL-37 and interfero...
Anti-Infective Agents Recombinant Proteins Antimicrobial Cationic Peptides Interferon-alpha Polyethylene Glycols Interferon alpha-2 Cathelicidins
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The Diagnostic Role of Vitamin D and Cathelicidin Levels in Pelvic Inflammatory Disease.

Clinical laboratory Jan 1, 2015
BACKGROUND: The aim of this study was to evaluate the effect of 25-hydroxyvitamin D [25(OH)D] and cathelicidin levels on pelvic inflammatory disease [PID] in reproductive aged women.
Humans Prospective Studies Biomarkers Female Adult Vitamin D Antimicrobial Cationic Peptides Cathelicidins Pelvic Inflammatory Disease
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