AIMC Topic: Biomedical Research

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Knowledge Discovery from Biomedical Ontologies in Cross Domains.

PloS one
In recent years, there is an increasing demand for sharing and integration of medical data in biomedical research. In order to improve a health care system, it is required to support the integration of data by facilitating semantic interoperability s...

Biomedical event trigger detection by dependency-based word embedding.

BMC medical genomics
BACKGROUND: In biomedical research, events revealing complex relations between entities play an important role. Biomedical event trigger identification has become a research hotspot since its important role in biomedical event extraction. Traditional...

Model-Free Machine Learning in Biomedicine: Feasibility Study in Type 1 Diabetes.

PloS one
Although reinforcement learning (RL) is suitable for highly uncertain systems, the applicability of this class of algorithms to medical treatment may be limited by the patient variability which dictates individualised tuning for their usually multipl...

Machine learning, statistical learning and the future of biological research in psychiatry.

Psychological medicine
Psychiatric research has entered the age of 'Big Data'. Datasets now routinely involve thousands of heterogeneous variables, including clinical, neuroimaging, genomic, proteomic, transcriptomic and other 'omic' measures. The analysis of these dataset...

Using the Semantic Web for Rapid Integration of WikiPathways with Other Biological Online Data Resources.

PLoS computational biology
The diversity of online resources storing biological data in different formats provides a challenge for bioinformaticians to integrate and analyse their biological data. The semantic web provides a standard to facilitate knowledge integration using s...

A Fuzzy Permutation Method for False Discovery Rate Control.

Scientific reports
Biomedical researchers often encounter the large-p-small-n situations-a great number of variables are measured/recorded for only a few subjects. The authors propose a fuzzy permutation method to address the multiple testing problem for small sample s...

Large scale biomedical texts classification: a kNN and an ESA-based approaches.

Journal of biomedical semantics
BACKGROUND: With the large and increasing volume of textual data, automated methods for identifying significant topics to classify textual documents have received a growing interest. While many efforts have been made in this direction, it still remai...

A corpus of potentially contradictory research claims from cardiovascular research abstracts.

Journal of biomedical semantics
BACKGROUND: Research literature in biomedicine and related fields contains a huge number of claims, such as the effectiveness of treatments. These claims are not always consistent and may even contradict each other. Being able to identify contradicto...

Generation of open biomedical datasets through ontology-driven transformation and integration processes.

Journal of biomedical semantics
BACKGROUND: Biomedical research usually requires combining large volumes of data from multiple heterogeneous sources, which makes difficult the integrated exploitation of such data. The Semantic Web paradigm offers a natural technological space for d...