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Blastocyst

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Seeking arrangements: cell contact as a cleavage-stage biomarker.

Reproductive biomedicine online
RESEARCH QUESTION: What can three-dimensional cell contact networks tell us about the developmental potential of cleavage-stage human embryos?

Deep Learning-Based Quantitative Blastocyst Assessment.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Selecting the single best blastocyst based on morphological appearance for implantation is a crucial part of in vitro fertilization (IVF). Various deep learning and computer vision-based methods have recently been applied for assessing blastocyst qua...

Deep-Learning Based Quantification of Bovine Oocyte Quality From Microscopy Images.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
The success rate of bovine in vitro embryo reproduction is low and highly dependent on the oocyte quality. The selection of the oocyte to be fertilized is done by the embryologists' visual examination of oocytes. It is time-consuming, subjective, and...

Improved pregnancy prediction performance in an updated deep-learning embryo selection model: a retrospective independent validation study.

Reproductive biomedicine online
RESEARCH QUESTION: What is the effect of increasing training data on the performance of ongoing pregnancy prediction after single vitrified-warmed blastocyst transfer (SVBT) in a deep-learning model?

The neglected emotional drawbacks of the prioritization of embryos to transfer.

Reproductive biomedicine online
In recent years, increasing efforts have been made to develop advanced techniques that could predict the potential of implantation of each single embryo and prioritize the transfer of those at higher chance. The most promising include non-invasive pr...

An artificial intelligence tool predicts blastocyst development from static images of fresh mature oocytes.

Reproductive biomedicine online
RESEARCH QUESTION: Can a deep learning image analysis model be developed to assess oocyte quality by predicting blastocyst development from images of denuded mature oocytes?

The morphokinetic signature of human blastocysts with mosaicism and the clinical outcomes following transfer of embryos with low-level mosaicism.

Journal of ovarian research
BACKGROUND: Genetic mosaicism is commonly observed in human blastocysts. Embryos' morphokinetic feature observed from time-lapse monitoring (TLM) is helpful to predict the embryos' ploidy status in a non-invasive way. However, morphokinetic research ...

A novel machine-learning framework based on early embryo morphokinetics identifies a feature signature associated with blastocyst development.

Journal of ovarian research
BACKGROUND: Artificial Intelligence entails the application of computer algorithms to the huge and heterogeneous amount of morphodynamic data produced by Time-Lapse Technology. In this context, Machine Learning (ML) methods were developed in order to...

BlastAssist: a deep learning pipeline to measure interpretable features of human embryos.

Human reproduction (Oxford, England)
STUDY QUESTION: Can the BlastAssist deep learning pipeline perform comparably to or outperform human experts and embryologists at measuring interpretable, clinically relevant features of human embryos in IVF?

Generative artificial intelligence to produce high-fidelity blastocyst-stage embryo images.

Human reproduction (Oxford, England)
STUDY QUESTION: Can generative artificial intelligence (AI) models produce high-fidelity images of human blastocysts?