AIMC Topic: Calmodulin

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Exploring voltage-gated sodium channel conformations and protein-protein interactions using AlphaFold2.

The Journal of general physiology Dec 18, 2025
Voltage-gated sodium (NaV) channels are vital regulators of electrical activity in excitable cells. Given their importance in physiology, NaV channels are key therapeutic targets for treating numerous conditions, yet developing subtype-selective drug...
Humans Models, Molecular Protein Conformation Ion Channel Gating Voltage-Gated Sodium Channels Calmodulin
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Adenosine Triphosphate Protects from Elevated Extracellular Calcium-Induced Damage in Human Proximal Kidney Cells: Using Deep Learning to Predict Cytotoxicity.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology Sep 21, 2022
BACKGROUND/AIMS: In kidney, extracellular [Ca] can modulate intracellular [Ca] to control key cellular processes. Hence, extracellular [Ca] is normally maintained within narrow range. We tested effect of extracellular ATP on viability of human proxim...
Humans Artificial Intelligence Deep Learning RNA, Messenger Kidney Calcium Adenosine Triphosphate Calcium Chloride Calmodulin Myeloid Cell Leukemia Sequence 1 Protein
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