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Fish-inspired tracking of underwater turbulent plumes.

Bioinspiration & biomimetics
Autonomous ocean-exploring vehicles have begun to take advantage of onboard sensor measurements of water properties such as salinity and temperature to locate oceanic features in real time. Such targeted sampling strategies enable more rapid study of...

Deep learning for contour quality assurance for RTOG 0933: In-silico evaluation.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE: To validate a CT-based deep learning (DL) hippocampal segmentation model trained on a single-institutional dataset and explore its utility for multi-institutional contour quality assurance (QA).

Deep active learning with high structural discriminability for molecular mutagenicity prediction.

Communications biology
The assessment of mutagenicity is essential in drug discovery, as it may lead to cancer and germ cells damage. Although in silico methods have been proposed for mutagenicity prediction, their performance is hindered by the scarcity of labeled molecul...

Relaxed stability criteria of delayed neural networks using delay-parameters-dependent slack matrices.

Neural networks : the official journal of the International Neural Network Society
This note aims to reduce the conservatism of stability criteria for neural networks with time-varying delay. To this goal, on the one hand, we construct an augmented Lyapunov-Krasovskii functional (LKF), incorporating some delay-product terms that ca...

Aperiodically intermittent quantized control-based exponential synchronization of quaternion-valued inertial neural networks.

Neural networks : the official journal of the International Neural Network Society
Inertial neural networks are proposed via introducing an inertia term into the Hopfield models, which make their dynamic behavior more complex compared to the traditional first-order models. Besides, the aperiodically intermittent quantized control o...

Bioinspired deformation computational design method for muscle-driven soft robots using MPM.

Bioinspiration & biomimetics
In order to adapt to complex and changing environments, animals have a wide variety of locomotor forms, which has inspired the investigation of their deformation and driving mechanisms. In this paper, we propose a computational design method for musc...

Approaching Optimal pH Enzyme Prediction with Large Language Models.

ACS synthetic biology
Enzymes are widely used in biotechnology due to their ability to catalyze chemical reactions: food making, laundry, pharmaceutics, textile, brewing─all these areas benefit from utilizing various enzymes. Proton concentration (pH) is one of the key fa...

Comprehensive modeling of corkscrew motion in micro-/nano-robots with general helical structures.

Nature communications
Micro-/nano-robots (MNRs) have impressive potential in minimally invasive targeted therapeutics through blood vessels, which has disruptive impact to improving human health. However, the clinical use of MNRs has yet to happen due to intrinsic limitat...

Asynchronous iterative Q-learning based tracking control for nonlinear discrete-time multi-agent systems.

Neural networks : the official journal of the International Neural Network Society
This paper addresses the tracking control problem of nonlinear discrete-time multi-agent systems (MASs). First, a local neighborhood error system (LNES) is constructed. Then, a novel tracking algorithm based on asynchronous iterative Q-learning (AIQL...

A stacking ensemble machine learning model for evaluating cardiac toxicity of drugs based on in silico biomarkers.

CPT: pharmacometrics & systems pharmacology
This study addresses the critical issue of drug-induced torsades de pointes (TdP) risk assessment, a vital aspect of new drug development due to its association with arrhythmia and sudden cardiac death. Existing methodologies, particularly those reli...