BACKGROUND: It is unclear which terms should be included in bibliographic searches for randomized controlled trials (RCTs) of drugs, and identifying relevant drug terms can be extremely laborious. The aim of our analysis was to determine whether a bi...
Networks are well suited to display and analyze complex systems that consist of numerous and interlinked elements. This study aimed at: (1) generating a series of drug prescription networks (DPNs) displaying co-prescription in community-dwelling elde...
IEEE/ACM transactions on computational biology and bioinformatics
Jan 1, 2015
Relative terms often appear together in the literature. Methods have been presented for weighting relativity of pairwise terms by their co-occurring literature and inferring new relationship. Terms in the literature are also in the directed acyclic g...
IEEE/ACM transactions on computational biology and bioinformatics
Jan 1, 2015
Discovering gene regulatory networks from data is one of the most studied topics in recent years. Neural networks can be successfully used to infer an underlying gene network by modeling expression profiles as times series. This work proposes a novel...
IEEE/ACM transactions on computational biology and bioinformatics
Jan 1, 2015
With the rapid development of biomedical sciences, a great number of documents have been published to report new scientific findings and advance the process of knowledge discovery. By the end of 2013, the largest biomedical literature database, MEDLI...
International journal of bioinformatics research and applications
Jan 1, 2015
This paper aims to enlighten the complex etiology beneath obesity by analysing data from a large nutrigenetics study, in which nutritional and genetic factors associated with obesity were recorded for around two thousand individuals. In our previous ...
International journal of data mining and bioinformatics
Jan 1, 2015
The scarcity of large labelled datasets comprising clinical text that can be exploited within the paradigm of supervised machine learning creates barriers for the secondary use of data from electronic health records. It is therefore important to deve...
International journal of data mining and bioinformatics
Jan 1, 2015
Prediction of different classes within the human leukocyte antigen (HLA) gene family can provide insight into the human immune system and its response to viral pathogens. Therefore, it is desirable to develop an efficient and easily interpretable met...
International journal of data mining and bioinformatics
Jan 1, 2015
Analysing and classifying sequences based on similarities and differences is a mathematical problem of escalating relevance and importance in many scientific disciplines. One of the primary challenges in applying machine learning algorithms to sequen...
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