AIMC Topic: Desipramine

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Machine learning-based model for behavioural analysis in rodents applied to the forced swim test.

Scientific reports
The Forced Swim Test (FST) is a widely used preclinical model for assessing antidepressant efficacy, studying stress response, and evaluating depressive-like behaviours in rodents. Over the last 10 years, more than 5500 scientific articles reporting ...

Machine-Learning Assisted Screening of Correlated Covariates: Application to Clinical Data of Desipramine.

The AAPS journal
Stepwise covariate modeling (SCM) has a high computational burden and can select the wrong covariates. Machine learning (ML) has been proposed as a screening tool to improve the efficiency of covariate selection, but little is known about how to appl...