BACKGROUND: A major obstacle in single-cell sequencing is sample contamination with foreign DNA. To guarantee clean genome assemblies and to prevent the introduction of contamination into public databases, considerable quality control efforts are put...
MOTIVATION: Bulk tumor samples used for high-throughput molecular profiling are often an admixture of cancer cells and non-cancerous cells, which include immune and stromal cells. The mixed composition can confound the analysis and affect the biologi...