AIMC Topic: Drug Contamination

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Environmental contamination, product contamination and workers exposure using a robotic system for antineoplastic drug preparation.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
Environmental contamination, product contamination and technicians exposure were measured following preparation of iv bags with cyclophosphamide using the robotic system CytoCare. Wipe samples were taken inside CytoCare, in the clean room environment...

Machine learning-assisted classification and adulteration detection of fatty oils using fatty acid profiles obtained via supercritical fluid chromatography.

Journal of pharmaceutical and biomedical analysis
Fatty oils are essential in the pharmaceutical field for enhancing the solubility and oral bioavailability of drugs, as well as reducing the risk of cardiovascular diseases. Consequently, detecting adulteration in specific fatty oils is critical to e...

Efficacy of an Automated Robotic Cleaning Device for Compounding Pharmacies.

International journal of pharmaceutical compounding
Compounded medicinal products should be prepared using an appropriate quality-assurance system. Cleaning and disinfection, as part of this system, are important to avoid cross-contamination of the preparations, reduce the bioburden levels in products...

Digital image technology based on PCA and SVM for detection and recognition of foreign bodies in lyophilized powder.

Technology and health care : official journal of the European Society for Engineering and Medicine
BACKGROUND: Digital image technology has made great progress in the field of foreign body detection and classification, which is of great help to drug purity extraction and impurity analysis and classification.

Acute keratoconjunctivitis due to contamination of contact lens care solution with histamine-producing Raoultella species: A case report.

Medicine
RATIONALE: Contact lens storage cases are known to be contaminated by a significant number of bacteria. However, histamine-producing Raoultella species has not been reported to contaminate contact lens storage case.

Development and validation of a stability-indicating reverse phase ultra performance liquid chromatographic method for the estimation of nebivolol impurities in active pharmaceutical ingredients and pharmaceutical formulation.

Se pu = Chinese journal of chromatography
A sensitive, stability-indicating gradient reverse phase ultra performance liquid chromatographic method has been developed for the quantitative estimation of nebivolol impurities in active pharmaceutical ingredient (API) and pharmaceutical formulati...