AIMC Topic: Early Termination of Clinical Trials

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Comparison of the completed and discontinued pediatric drug clinical trials in Mainland China: a cross-sectional analysis based on the data from 2003 to 2023.

BMC pediatrics Oct 13, 2025
BACKGROUND: Pediatric drug clinical trials are essential for ensuring the accessibility and safety of medications intended for children. In recent years, the Chinese government has implemented various measures to foster the development of pediatric d...
Humans Cross-Sectional Studies China Child Pediatrics Clinical Trials as Topic Early Termination of Clinical Trials
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Latent Dirichlet Allocation in predicting clinical trial terminations.

BMC medical informatics and decision making Nov 27, 2019
BACKGROUND: This study used natural language processing (NLP) and machine learning (ML) techniques to identify reliable patterns from within research narrative documents to distinguish studies that complete successfully, from the ones that terminate....
Humans Machine Learning Databases, Factual Models, Theoretical Narration Natural Language Processing Clinical Trials as Topic Early Termination of Clinical Trials
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Lessons learned from conducting a pragmatic, randomized, crossover trial on robot-assisted gait training in children with cerebral palsy (PeLoGAIT).

Journal of pediatric rehabilitation medicine Jan 1, 2020
PURPOSE: To investigate the effectiveness of outpatient robot-assisted gait training (RAGT) in ambulatory children with spastic cerebral palsy.
Humans Female Male Adolescent Child Treatment Outcome Follow-Up Studies Robotics Gait Cross-Over Studies Cerebral Palsy Orthotic Devices Physical Therapy Modalities Walk Test Early Termination of Clinical Trials
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